Description
SLAM family member 6, also known as SLAMF6, belongs to the SLAM family of immune cell receptors. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. SLAMF6 is expressed on NK-, T-, and B cells. It exhibits homotypic interactions and can associate with adaptor molecules such as SAP to modulate immune cell functions. Recombinant human SLAMF6 protein, fused to His-tag at N-terminus, was expressed in E.coli